We started transdermal chelation last weekend. It wasn't as scary as I anticipated but it was exhausting. We began Friday morning and dosed every 8 hours around the clock until Sunday night (well, it was really Monday morning). I had to mix and apply the creams to various parts of Matthew's body (where the skin is thin)...1/4 ml of DMSA with IPM and 1/4 ml Glutathione with it's IPM. I must wear gloves which Matthew is afraid of b/c they remind him of blood draws, but he is getting better with them. The hardest part for me was having to wake in the middle of the night to mix/apply the cream.
The schedule we use is 3 days on, 11 days off and we'll always do it on weekends so I can monitor his reaction. I was expecting a rash (a somewhat common reaction) at the application sites but he didn't have any. (Thankfully, he is not allergic to sulphur.) The only difference I noticed was that he was more tired/crabby on the 2nd and third day and then for 2 days after that. On the 11 days "off" I'll continue to give him his daily Glutathione cream at a larger dose (1 ml)...this helps with detox.
From what I've read, it usually takes anywhere from 1 to 3 years to chelate a child with heavy metal poisoning...hopefully it won't take too long for Matthew. He is young (almost 3.5) and has less exposure than older kids (especially the children that were clobbered with thimerosal during the 1990's). We'll keep doing the DMSA cream until we don't see good "pulls" (of metals in the urine/stool tests) any longer and then I think we'll ask for DMSA and/or ALA in capsule form (which I could mix in his juice). I know suppositories and IV chelation would get bigger pulls/faster results but I'm just not interested in doing those right now...besides our DAN doesn't do IV's and Matthew wouldn't let anyone put one in him!
P.S. Here's the link to the pharmacy/product we are using: http://www.leesilsby.com/dmsa.php